Prisma Health is one of the Southeast’s leading health care providers, nationally recognized for advanced technology, innovative research and teaching excellence. The system’s seven campuses include a Level 1 Trauma Center, six acute care hospitals (including a short-stay surgical hospital), a psychiatric hospital, a rehabilitation hospital, a long-term acute care hospital and numerous outpatient facilities.

Prisma Health is a community-university model. Having grown over its 100 years from a single community hospital to a comprehensive, integrated delivery system, Prisma Health is focused on high-volume, high-quality patient care enhanced by education and research. Because of its history, Prisma Health is the ideal “community-university” model of resident education to give you hands-on patient care experience augmented by the advantages of our role as an academic health center.


  • High patient volumes
  • Real-world experience from the first day
  • State-of-the-art facilities
  • Extensive research opportunities
  • Supportive faculty-resident interaction
  • Great quality of life in the Greenville community

Prisma Health–Upstate/University of South Carolina Residency Programs in the Office of Graduate Medical Education and Residency Affairs offer primary care experience as well as specialty and sub-specialty rotations found in university programs. Residents receive a broad-based education with a personal touch from attending faculty and community physicians. While volume, technology, professional expertise and research are important, personal care and customer service are emphasized.

In mentoring residents, we strive to create an appropriate balance between providing supervision and granting independence in patient care. We view our residents as practicing physicians and, consequently, expect them to be committed both to providing the best of care and to learning all they can.

Prisma Health is affiliated with the Medical University of South Carolina (MUSC) and the University of South Carolina School of Medicine (USCSOM). Our fully accredited residency programs currently include 259 residents in 13 programs.

In 2006, Prisma Health became the 97th member to join University HealthSystem Consortium (UHC). To become a part of UHC requires demonstrating excellence in service and teaching.

In 2010, Prisma Health received National Accreditation for its human research protection program (IRB and Research Compliance) from the Association for the Accreditation of Human Research Protection Program (AAHRPP).

Click here to view the Office of Graduate Medical Education House Staff Manual for
academic year 2020 – 2021.